* { margin: 0; padding: 0; box-sizing: border-box; }
body { font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif; background: #f5f7fa; color: #2c3e50; line-height: 1.6; }
.container { max-width: 860px; margin: 0 auto; padding: 0 20px 60px; }
.header { background: linear-gradient(135deg, #11998e 0%, #38ef7d 100%); color: white; padding: 48px 20px 40px; text-align: center; }
.header h1 { font-size: 2rem; font-weight: 700; margin-bottom: 8px; }
.subtitle { font-size: 1.05rem; opacity: 0.9; font-weight: 300; }
.medical-disclaimer { background: #fff3cd; border: 1px solid #ffc107; border-radius: 8px; padding: 14px 16px; margin: 24px 20px 0; font-size: 0.88rem; color: #856404; max-width: 820px; margin-left: auto; margin-right: auto; }
.ad-space { margin: 24px auto; min-height: 90px; }
.card { background: white; border-radius: 12px; padding: 32px; box-shadow: 0 2px 12px rgba(0,0,0,0.07); border: 1px solid #eee; margin: 24px 0; max-width: 820px; margin-left: auto; margin-right: auto; }
.drug-input-row { display: flex; gap: 8px; margin-bottom: 12px; align-items: center; }
.drug-input { flex: 1; padding: 11px 14px; border: 1.5px solid #dde2e8; border-radius: 8px; font-size: 0.95rem; color: #2c3e50; background: white; }
.drug-input:focus { outline: none; border-color: #11998e; }
.remove-btn { background: none; border: 1px solid #ddd; color: #e74c3c; border-radius: 6px; padding: 8px 12px; cursor: pointer; font-size: 0.9rem; }
.add-btn { background: none; border: 2px dashed #11998e; color: #11998e; padding: 10px 20px; border-radius: 8px; font-size: 0.9rem; font-weight: 600; cursor: pointer; margin-top: 4px; display: block; width: 100%; transition: all 0.2s; }
.add-btn:hover { background: #11998e10; }
.calc-btn { width: 100%; padding: 14px; background: linear-gradient(135deg, #11998e, #38ef7d); color: white; border: none; border-radius: 8px; font-size: 1rem; font-weight: 700; cursor: pointer; margin-top: 16px; color: #1a3a2a; }
.calc-btn:hover { opacity: 0.9; }
.results { max-width: 820px; margin: 0 auto; }
.results.show { display: block !important; }
.interaction-card { background: white; border-radius: 12px; padding: 24px; margin-bottom: 16px; box-shadow: 0 2px 12px rgba(0,0,0,0.07); border-left: 4px solid #eee; }
.interaction-card.major { border-left-color: #e74c3c; }
.interaction-card.moderate { border-left-color: #f39c12; }
.interaction-card.minor { border-left-color: #27ae60; }
.interaction-header { display: flex; align-items: center; gap: 10px; margin-bottom: 12px; }
.severity-badge { padding: 3px 10px; border-radius: 20px; font-size: 0.78rem; font-weight: 700; text-transform: uppercase; }
.severity-badge.major { background: #ffeaea; color: #e74c3c; }
.severity-badge.moderate { background: #fff8e6; color: #f39c12; }
.severity-badge.minor { background: #f0fff4; color: #27ae60; }
.drug-pair { font-weight: 700; font-size: 1rem; color: #2c3e50; }
.interaction-desc { color: #555; font-size: 0.9rem; line-height: 1.7; }
.no-interaction { background: #f0fff4; border-radius: 12px; padding: 24px; text-align: center; color: #27ae60; font-weight: 600; margin-bottom: 16px; }
.spinner { width: 32px; height: 32px; border: 3px solid #eee; border-top-color: #11998e; border-radius: 50%; animation: spin 0.8s linear infinite; margin: 0 auto; }
@keyframes spin { to { transform: rotate(360deg); } }
.drug-tag { display: inline-block; background: #f0fff4; border: 1px solid #11998e40; color: #11998e; padding: 4px 10px; border-radius: 20px; font-size: 0.82rem; font-weight: 600; margin: 2px; }
.info-section { background: white; border-radius: 12px; padding: 32px; margin: 24px auto; max-width: 820px; box-shadow: 0 2px 12px rgba(0,0,0,0.06); border: 1px solid #eee; }
.info-section h2 { font-size: 1.2rem; margin-bottom: 12px; }
.info-section p { color: #555; font-size: 0.93rem; line-height: 1.75; margin-bottom: 10px; }
.footer { text-align: center; padding: 32px 20px; background: #2c3e50; color: #bdc3c7; font-size: 0.88rem; margin-top: 40px; }
.footer a { color: #bdc3c7; text-decoration: none; }
.footer a:hover { color: white; }
@media (max-width: 600px) { .header h1 { font-size: 1.5rem; } .card { padding: 20px 16px; } }